Langerhans Cell Histiocytosis of the Uvea with a Ciliochoroidal Mass: A Case Report of Management with Systemic Therapy

Langerhans Cell Histiocytosis of the Uvea with a Ciliochoroidal Mass: A Case Report of Management with Systemic Therapy

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Background.This study is aimed at exploring a case of choroidal Langerhans cell histiocytosis (LCH) successfully treated with systemic Headwear corticosteroid and immunosuppressant.Case presentation.A 24-year-old man with known multisystem LCH developed loss of vision, ocular pain, conjunctival injection, panuveitis, and a ciliochoroidal mass.After receiving an intravenous methylprednisolone pulse, oral high-dose corticosteroids, and methotrexate, the mass resolved quickly and completely without flare-ups during 6 months of follow-up.

Conclusions.Intraocular involvement of LCH is rare and can present with or without a history of multisystemic disease.The diagnosis is challenging, and the standard treatment is not established.Systemic anti-inflammatory and immunosuppressive therapy could be an Me Swimsuit effective treatment, as the LCH itself contains an essential element of inflammation and the symptoms may be mainly inflammatory.